CancerTracer: a curated database for Intrapatient Tumor Heterogeneity
●Results:
| Cancer Type | Patient Details | Trunk Mutation | Branch Mutation | Private Mutation |
|---|
| Thyroid Cancer | p081_p1 | EIF1AX(p.P2R),FOLH1B(p.V91M),ZNF521(p.T357M),IFT140(p.Y1414fs),IFT140(p.M1411fs) |
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CAPN15(p.D785N),SLC2A4(p.R246H),MIDN(p.L73F),GCDH(p.K334N),DUOXA2(p.A217G),JPH4(p.G547E),TRPM1(p.K315I),HIPK1(p.R1068C),AIM1(p.V1469M),GLCE(p.G433V),WBP2NL(p.F94Y),NRAS(p.D51R),MOD2(p.118_119del),OR4P4(p.I204F),MBOAT1(p.G316R),EXOC1(p.D605H),INTS5(p.D436E),GRAMD4(p.S33G),TBATA(p.E321K),KIF1B(p.I38T),TXNDC8(p.Q50X),TINF2(p.G326E),SP4(p.P531A),AUTS2(p.P361L),TYR(p.N57T),EP300(p.P505A),GALE(p.R58C),KIAA0141(p.N177S),ATG13(p.Y220F),ZNF70(p.G220R),PDGFRB(p.N666K),MOGAT3(p.E305K),TP53(p.S260fs),ADRA2B(p.H402fs),MON2(p.E1108K),BPTF(p.Q2502K),OR8H2(p.F63V),FCGBP(p.E937Q),SHCBP1(p.W23X),RGS12(p.I84F),L3MBTL2(p.H70fs),PTBP1(p.A54T),TP53(p.A138V),L3MBTL2(p.S67fs) |
| Thyroid Cancer | p081_p2 | CXorf21(p.E151X),ZNF365(p.R387C),USP9X(p.L1306fs),GLI2(p.E735X),SLC9C1(p.F8C),GLO1(p.P133S),N4BP2L1(p.F91L),SOX9(p.Q505H),CDC42EP1(p.S260P),BRAF(p.V600E),ARFGAP2(p.386_387del),KMT2C(p.G1815D),PER3(p.A1007T),PHKB(p.L114V),VPS13B(p.V3872fs),PER3(p.K998E),ARHGEF40(p.A157S) |
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SCAF11(p.E926fs),SRRM3(p.202_201del),IGSF9(p.L52fs),ACE(p.E154Q),PCNX(p.Q537N),CST3(p.D145N),NR4A3(p.97_98del),TRPM7(p.F71L),GPR116(p.Q741E),TMEM101(p.A92V),SETDB2(p.E618K),SAA1(p.H112L),TMTC2,OR12D3(p.L211V),SSUH2(p.N261I),AGRN(p.D1501N),TG(p.C1264R),EPHB2(p.M740I),PTBP1(p.D43H),OSBPL3(p.S172L),PELI3(p.R322Q),JAK2(p.L967V),METTL13(p.D54H),ZNF423(p.D358N),JAK2(p.Q942X),SPRR3(p.54_62del),COL28A1(p.L881P),STAT6(p.L560F),GMPPB(p.T153R),CDC42EP1(p.A256T),TP53(p.C135Y),EYA1(p.S102F),MS4A7(p.G183C),ADCY10(p.H976N),NOX5(p.E552D),SP140(p.E386K),PIK3CA(p.H1047L),TSR3(p.F28L),BCOR(p.H1126D),WDR45(p.S210L),ATN1(p.P786L) |
| Thyroid Cancer | p081_p3 | MSH3(p.A68A),CKB(p.R152R),MAML2(p.Q596Q) |
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PFN2(p.W4G),SLC35F1(p.I282T),DIS3(p.D487G),SYT9(p.G320C),PKHD1(p.S3669L),INSIG2(p.R110L),DCLK1(p.P335H),ALDH1L2(p.R773L),DPP10(p.R87L),SEC14L4(p.G86C),AKAP4(p.F643L),SH3BP(p.Q690E),MYH3(p.Q1382K),MAP1S(p.E216K),ABCB8(p.V156L),PIK3CA(p.E545K),NHS(p.S1005X),HOXA4(p.G31S),USP18(p.D157N),TBX2(p.E655K),GP6(p.S117L),EPHX4(p.Y325C),ADRA2A(p.T161M),IFT172(p.E454K),LRP1B(p.E246K),GLTSCR1L(p.D5N),AFAP1(Q72E),ACSL1(p.K614R),TAF1(p.K551N),NCOR1(p.E562K),ASB1(p.L318V),EPS15(p.Q479X),STRN4(p.L178F),MMA4(p.D344N),GSX1(p.E179K),DOPEY2(p.M2010I),CCNT1(p.F14L),CASC3(p.S21L),PDZD7(p.E506Q),DYNC1LI1(p.R6P),CARD11(p.R179Q),RPGRIP1L(p.R513K),ATP2B2(p.E645Q),STAB2(p.G1481Q),RFTN2(p.E483X),FANCA(p.R1195L),CDR1(p.G170A),TP53(p.S241F),CCNB3(p.E836Q),TRAPPC8(p.L406M),MAPK8(p.R263K) |
| Papillary Thyroid Cancer | p092_case | ATIC(Chr2:216203530:A>G),BHLHE40(Chr3:5025066:C>G),C6orf211(Chr6:151779468:C>T),C8orf42(Chr8:442554:C>G),DNAJC30(Chr7:73097567:C>T),ERGIC1(Chr5:172341742:G>C),FASTK(Chr7:150775693:T>C),FAT1(Chr4:187524338:A>G),FBXO44(Chr1:11718796:C>T),GFPT1(Chr2:69555414:C>T),HDAC7(Chr12:48187203:G>C),KIAA1370(Chr15:52901586:T>C),LAP3(Chr4:17606211:G>A),LTBP4(Chr19:41129562:G>A),NLN(Chr5:65058849:A>C),NLN(Chr5:65058859:C>T),NXF1(Chr11:62568613:C>A),OBSCN(Chr1:228565209:G>A),PCDHGA2(Chr5:140718566:T>C),RNF126(Chr19:648972:G>A),S100A5(Chr1:153509901:G>C),SCAMP4(Chr19:1923155:C>T),SMARCE1(Chr17:38785063:T>C),THOP1(Chr19:2807014:A>G),VPRBP(Chr3:51475844:G>T),XPO5(Chr6:43527938:C>T),ZNF148(Chr3:124951849:T>C) |
ACTL6A(Chr3:179304346:A>G),CNOT3(Chr19:54652265:C>T),DHX16(Chr6:30638611:C>A),EIF2AK1(Chr7:6064387:T>G) |
AMPD2(Chr1:110170817:G>T),TRNT1(Chr3:3170855:G>C) |
| Papillary Thyroid Cancer | p121_p083 | PTEN(p.R233*),HRAS(p.Q61R) |
- |
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| Anaplastic Thyroid Cancer | p129_ATC01 | SPTA1(p.L793F),RAD51AP2(p.N745K),PRKCE(p.R402H),HNRNPA3(p.G280G),CASP8(p.S375C),PIK3CA(p.H1047R),FNDC1(p.H572H),BRAF(p.V600E),GCNT1(p.I104M),ARHGAP21(p.E1341K),VPS37C(p.E165Q),HNF1A(p.A174A),FANCM(p.T1759S),TICRR(p.L434F),CES5A(splicesite),PRAM1(p.E614Q),MUC16(p.A3309T),SMARCA4(p.E1669K),ZNF324B(p.Q513*),DUSP15(p.G274D),SRSF6(p.R255W),SLC9A8(p.T560M) |
NEK5(p.E598K),PIM3(p.G101G),BMPR2(p.I412V),ZACAN23(p.F286C),SUN1(frameshiftdel),SSBP3(p.P311P),ZYG11B(p.M545I),PATZ1(p.S124S),SLC17A7(p.S344F),FOXO1(p.S37L),RPL5(p.R58fs),KIFC2(p.R661C),TIMELESS(p.F472L),RPUSD2(p.P114R),RGPD1(p.K5K),IGSF11(p.P62P),RELL2(p.D55N),LRRC9(p.I810V),DCSTAMP(p.I245del),TREX1(p.P10S),USP7(p.Q4H),CCDC17(p.D76G) |
ADAMTS2(p.R598H),MIER1(p.G22splice),FLG(p.H2505R),FAM115C(p.H418H),FAM115C(p.W420R),NANOGNB(p.R5W),CCT2(p.K13E),GOLGA3(p.K1270E),CCDC168(p.F1300I),MKS1(p.E3K),VAV1(p.Y209C),NUF2(p.N360S),CCDC85A(p.A463G),ARHGEF4(p.E426K),USP40(p.R44I),ZNF501(p.A269T),GATAD1(p.K21N),PDILT(splicesite),PMEPA1(p.A11T),ARFGAP1(p.S319L),FLG(p.P3298A),FLG(p.A704P),TRAPPC12(p.I348I),TRAPPC12(p.Q349K),BOD1L1(p.M878L),GUF1(p.S352P),EYS(p.H1025R),COL9A1(p.S203P),CD6(p.393_396NKES>T),TBXA2R(p.P352P),SRRM5(p.S79P),MYO18B(p.R1254C),DPYSL5(p.A236A_silent),SPTBN1(p.P593P_silent),POM121L2(p.P198P_silent),PXDNL(p.C184S),IGSF22(p.K1258N),CCDC122(p.Q270Q_silent),C14orf178(p.S63N),VPS53(p.P749L),SERPINB12(p.Y115H),ICOSLG(p.A439A_silent),KRTAP10-5(p.S11G),KRTAP10-5(p.T5T_silent),WDR64(p.R8H),STK36(p.S522Y),CBLB(p.H10H_silent),SMG1(p.G13S),FLG(p.R3240H),OR4D11(p.Y123*),RASL10A(p.R172C),CCDC142(p.E506K),SP9(p.A462A_silent),KLHL30(p.A374A_silent),MAZ(p.A160A_silent) |
